Fluconazole is indicated in adults for the treatment of: Cryptococcal meningitis, Coccidioidomycosis. Invasive candidiasis. Mucosal candidiasis (including oropharyngeal candidiasis, esophageal candidiasis, candiduria and cutaneous mucus candidiasis). Chronic atrophic oral candidiasis (dental prosthesis stomatitis) in cases where dental hygiene and topical treatment are insufficient. Fluconazole is indicated in adults for prophylaxis of recurrence of cryptococcal meningitis in patients at high risk of relapse.